Table 4 Mammographic density in relation to selected SNPs
From: TNRC9 rs12443621 and FGFR2 rs2981582 polymorphisms and breast cancer risk
SNP | Genotype | Mammographic density | χ 2 | P | ||||
|---|---|---|---|---|---|---|---|---|
Category 1 | Category 2 | Category 3 | Category 4 | Total | ||||
TNRC9 | AA | 5(9.26) | 27(50) | 20(37.04) | 2(3.70) | 54 | 0.502 | 0.778 |
rs12443621 | GG | 7(3.83) | 96(52.46) | 74(40.44) | 6(3.28) | 183 | ||
AG | 4(4.84) | 42(51.22) | 34(41.46) | 2(2.44) | 82 | |||
Total | 16(5.02) | 165(51.72) | 128(40.13) | 10(3.13) | 319 | |||
FGFR2 | GG | 8(6.72) | 71(59.66) | 36(30.25) | 4(3.36) | 119 | 6.752 | 0.0342 |
rs2981582 | GA | 4(3.64) | 53(48.18) | 49(44.55) | 4(3.64) | 110 | ||
AA | 4(4.44) | 41(45.56) | 43(47.78) | 2(2.22) | 90 | |||
Total | 16(5.02) | 165(51.72) | 128(40.13) | 10(3.13) | 319 | |||
TNRC9 | CC | 14(6.45) | 110(50.69) | 85(39.17) | 8(3.69) | 217 | 1.1661 | 0.5582 |
rs3803662 | CT | 2(2.63) | 38(50) | 34(44.74) | 2(2.63) | 76 | ||
TT | 0(0) | 17(65.38) | 9(34.62) | 0(0) | 26 | |||
Total | 16(5.02) | 165(51.72) | 128(40.13) | 10(3.13) | 319 | |||
LSP1 | TT | 10(4.17) | 128(53.33) | 92(38.33) | 10(4.17) | 240 | 0.654 | 0.7211 |
rs3817198 | CT | 4(5.80) | 33(47.83) | 32(46.38) | 0(0) | 69 | ||
CC | 2(20) | 4(40) | 4(40) | 0(0) | 10 | |||
Total | 16(5.02) | 165(51.72) | 128(40.13) | 10(3.13) | 319 | |||