Table 3 CDK5 expression associated with the various clinicopathological parameters in lung cancer
Lung cancer | n | CDK5 negative (n, %) | CDK5 positive (n, %) | Z | P |
|---|---|---|---|---|---|
Gender | −0.884 | 0.377 | |||
Male | 275 | 137(49.8) | 138(50.2) | ||
Female | 90 | 40(44.4) | 50(55.6) | ||
Age(years) | −0.418 | 0.676 | |||
<60 | 196 | 96(49.0) | 100(51.0) | ||
≥60 | 169 | 81(47.9) | 88(52.1) | ||
Pathological grading | 25.060a | <0.001 | |||
I | 39 | 29(74.4) | 10(25.6) | ||
II | 92 | 53(57.6) | 39(42.4) | ||
III | 131 | 44(33.6) | 87(66.4) | ||
TNM | −2.944 | 0.003 | |||
I–II | 299 | 156(52.2) | 143(47.8) | ||
III–IV | 63 | 20(31.7) | 43(68.3) | ||
LNM | −7.080 | <0.001 | |||
Yes | 128 | 30(23.4) | 98(76.6) | ||
No | 234 | 146 (62.4) | 88(37.6) | ||
Tumor diameter (cm) | −1.653 | 0.098 | |||
≤7 | 314 | 158(50.3) | 156(49.7) | ||
>7 | 48 | 18(37.5) | 30(62.5) | ||
Distal metastasis | −1.931 | 0.054 | |||
Absent | 346 | 172(49.7) | 174(50.3) | ||
Present | 16 | 4(25.0) | 12(75.0) |