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Table 2 Uni- and multivariate analyses for prognosis

From: A clinical role of staging laparoscopy in patients with radiographically defined locally advanced pancreatic ductal adenocarcinoma

Variable Univariate analysis Multivariate analysis
  p Hazard ratio (95 % CI) Estimate SE p Hazard ratio (95 % CI))
CR/PR vs SD/PD <0.001 0.23 (0.12–0.45) −1.30 0.37 <0.001 0.27 (0.13–0.56)
Second-line chemotherapy none vs done <0.001 3.60 (2.03–6.37) 0.98 0.40 0.013 2.67 (1.23–5.78)
GS none vs done 0.009 2.05 (1.19–3.52) 0.21 0.34 0.53 1.24 (0.64–2.39)
Radiation none vs done 0.009 2.21 (1.22–4.01) 0.13 0.39 0.73 1.14 (0.53–2.45)
No ascites vs development of ascites at 1 year <0.001 0.39 (0.23–0.65) −0.12 0.31 0.70 0.89 (0.48–1.63)
LA/CY vs P/L 0.015 0.51 (0.30–0.88) −0.11 0.32 0.72 0.89 (0.48–1.68)
  1. CI confidential interval, SE standard and error, CR complete response, PR partial response, SD stable disease, PD progressive disease, GS gemcitabine and S-1, LA locally advanced, CY positive cytology, P peritoneal metastasis, L liver metastasis, CTx chemotherapy, BSC best supportive care