Fig. 3

Effect of endostatin/CTX on the notch signaling protein expression. The figure shows the western blot analysis of notch signaling proteins NOTCH-3, JAG-1, and DLL-4 following endostatin/CTX treatment. E represents endostatin and CTX represents cyclophosphamide. The four lanes represent three treatment concentrations (E at 15, 10, and 5 mg/kg/day, CTX at 20, 10, and 5 mg/kg/day and E + CTX at 15 + 20, 15 + 10, and 15 + 5 mg/kg/day) plus control. β-actin acts as the internal control. a NOTCH-3, JAG-1, and DLL-4 expression in E, C, E + C-treated samples. b Notch signaling protein expression in different colorectal cell lines (HCT-116, SW-480, SW-620)