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Table 5 Summary of localization procedures

From: Localization of nonpalpable pulmonary nodules using CT-guided needle puncture

Method

Advantage

Disadvantage

Ref.

CT-guided hookwire

Safe, fast

Chest wall pain, pneumothorax

[7, 1315]

Low complication rate

Dislodgement

CT-guided coil

Same as above

Lung parenchyma damage

[8]

Coil migration

CT-guided barium spray

Same as above

Inflammatory reaction of tissue

[911]

Intraoperative ultrasound

Quick

Difficult for emphysematous lung

[12, 18, 19]

More affordable

For lesion more than 1 cm

Less invasive

Operator dependent

Methylene blue

Simple

Diffuse into surrounding lung

[19, 20]

Inexpensive

Fluoroscopic-aided contrast medium

Adequate margins of resections on fluoroscopic imaging

Contrast allergy

[2123]

Radiation exposure

Pneumothorax

Radio-guided thoracoscopic surgery

Real-time verifying stapled margin

Gamma ray detector

[24]

Diffusion or pleural spillage

Short half-life

Bronchoscopic metallic coil marking

Avoid pneumothorax, secondary hematoma, and the intravascular injection of substances originating in needling

Ultrathin bronchoscope

[25]

C-arm use

Metallic allergy

Coil migration, cost

CT-guided puncture

No dye, radiotracer, or contrast medium

Cooperation with radiologist

This study

No migration

Technique dependent

  1. Ref reference