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Table 3 Influence of interaction between living habits and genetic polymorphisms on the risk of CRC

From: Genetic polymorphisms in XRCC1 genes and colorectal cancer susceptibility

Factor 1 Factor 2 Controls (%) Cases (%) χ 2 value OR 95 % CI
Total smoking amount Arg194Trp      
Never smoking Trp/Trp 25 (7.14) 13 (4.06) 1
Slight smoking Arg/Trp + Arg/Arg 77 (22.0) 56 (17.5) 0.765 1.40 0.66–2.97
Heavy smoking Arg/Trp + Arg/Arg 47 (13.4) 71 (22.2) 7.794 2.91 1.35–6.24
Total smoking amount Arg280His      
Never smoking Arg/Arg 160 (45.7) 116 (36.3) 1
Slight smoking Arg/His + His/His 28 (8.00) 22 (6.88) 0.067 1.08 0.59–1.99
Heavy smoking Arg/His + His/His 15 (4.29) 18 (5.63) 1.880 1.66 0.80–3.42
Total smoking amount Arg399Gln      
Never smoking Arg/Arg 130 (37.1) 81 (25.3) 1
Slight smoking Arg/Gln + Gln/Gln 37 (10.6) 30 (9.38) 0.865 1.30 0.75–2.27
Heavy smoking Arg/Gln + Gln/Gln 23 (6.57) 39 (12.2) 11.69 2.72 1.52–4.89
Drinking habit Arg194Trp      
No Trp/Trp 32 (9.14) 19 (5.94) 1
Yes Arg/Trp + Arg/Arg 56 (16.0) 64 (20.0) 3.704 1.93 0.98–3.77
Drinking habit Arg280His      
No Arg/Arg 213 (60.9) 173 (54.1) 1
Yes Arg/His + His/His 21 (6.00) 28 (8.75) 2.657 1.64 0.90–2.99
Drinking habit Arg399Gln      
No Arg/Arg 166 (47.4) 108 (33.8) 1
Yes Arg/Gln + Gln/Gln 21 (6.00) 27 (8.44) 4.754 1.98 1.06–3.67
  1. The Italic type meant: this part of data had statistical significance