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Table 5 The correlations between the overall survival and various clinicopathological factors

From: The prognostic significance of a postoperative systemic inflammatory response in patients with colorectal cancer

  Univariate analysis Multivariate analysis
  Hazard ratio 95 % CI p value Hazard ratio 95 % CI p value
Age (>70 years) 2.113 1.142–3.911 0.017 0.912 0.204–4.083 0.904
Gender (Male) 0.684 0.361–1.295 0.243    
Location of primary tumor (Colon) 0.749 0.404-1.389 0.360    
Tumor depth (T4) 1.863 1.007–3.448 0.048 4.592 0.896–23.544 0.068
Histological type (Poorly, mucinous) 3.449 1.582–7.518 0.002 0 0 0.988
Lymphatic involvement (Positive) 2.744 0.839–8.979 0.095    
Venous involvement (Positive) 2.102 1.080–4.093 0.029 0.350 0.068–1.800 0.209
Number of lymph node metastases 2.924 1.816–4.707 <0.001 14.677 2.571–83.779 0.003
Preoperative CEA (>5 ng/ml) 1.939 0.875–4.299 0.103    
Preoperative CA19-9 (>37 U/ml) 1.298 0.176–9.586 0.798    
Adjuvant chemotherapy (Yes) 0.332 0.080–1.384 0.130    
Chemotherapy regimen (with oxaliplatin) 0.726 0.216–2.433 0.603    
Postoperative NLR (>3.0) 3.597 1.643–7.875 0.001 15.713 1.590–155.227 0.018
Postoperative GPS (≥1) 1.982 0.933–4.208 0.075    
Preoperative NLR (>2.5) 2.204 1.023–4.750 0.044 6.599 0.928–46.914 0.059
Preoperative GPS (≥1) 2.723 1.372–5.404 0.004 7.238 1.180–44.415 0.032
  1. CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19-9, NLR neutrophil-to-lymphocyte ratio, CRP C-reactive protein, GPS Glasgow prognostic score