Table 1 Up-to-date review of the current literature - primary mediastinal neuroblastoma
From: Ataxia induced by a thymic neuroblastoma in the elderly patient
Patient number | Primary site | Age/sex | Treatment | Size | Presenting symptom | n-myc amplified | Metastases | Outcome | Ref |
|---|---|---|---|---|---|---|---|---|---|
1 | Left anterior mediastinum - thymus | 65/F | Surgery alone | 6.4 × 6.2 × 3.4 cm | None (abnormal CXR) | NA | None | NED at 15 months | Ueda et al. [9] |
2 | Left anterior mediastinum - thymus | 79/F | Surgery alone | 10 × 8 × 7 cm | SIADH, abnormal CXR | NA | None | NED at 24 months | Pellegrino et al. [7] |
3 | Thymus | 67/F | CABG + resection | 20 g | Coronary artery disease, SIADH | NA | NA | Died from VF POD 10 | Argani et al. [5] |
4 | Anterior mediastinal mass | 80/M | Surgery alone | 7.3 cm | NA | NA | NA | NED at 18 months | Argani et al. [5] |
5 | Anterior mediastinal mass | 71/F | Surgery alone | 630 g | Abnormal CXR + pleural effusion | NA | Local + distant | Died 1 year from extensive disease | Argani et al. [5] |
6 | Superior mediastinum | 64/M | Surgery + chemotherapy | 5 × 3 cm | None (abnormal CXR) | + | Lymph node | Lymph node metastases at 10 months | Ohtaki et al. [4] |
7 | Right anterior mediastinum - thymus | 60/M | Surgery alone | 4.7 cm | SIADH, Abnormal CXR | NA | None | NA | Ogawa et al. [6] |
8 | Anterior mediastinum | 80/F | Surgery + radiation therapy | 7 cm | SIADH | NA | None | NED at 14 months | Salter et al. [8] |
9 | Left anterior mediastinum | 86/M | Surgery alone | 5.2 × 4.7 cm | SIADH, abnormal CXR | NA | None | NED at 11 months | Rogowitz et al. [3] |
10 | Anterior mediastinum - thymus | 62/M | Surgery alone | 5.2 × 3.8 cm | Ataxia, visual disturbances | Negative | None | NED at 6 months | Present report |