Figure 3
From: Ataxia induced by a thymic neuroblastoma in the elderly patient
Histology, immunohistochemistry, and gross pathology of the resected specimen. (A) Histology of the mediastinal mass revealed a monotonous population of small- to medium-sized round cells with scant cytoplasm and finely granular chromatin within a background of neutrophils, consistent with the diagnosis of neuroblastoma (H&E, original magnification ×400). (B) Confirmatory immunohistochemistry (IHC) revealed diffuse synaptophysin positivity (original magnification ×400). (C) Pathologic specimen shows 7.5 × 5 × 3.7 cm, tan-white, lobulated, focally hemorrhagic, encapsulated resected anterior mediastinal mass.