Expression of ezrin, CD44, and VEGF in giant cell tumor of bone and its significance

Table 3 Relation between ezrin, CD44, and VEGF expressions in GCTB patients and their clinical pathological features

Clinical parameter	n	Ezrin		CD44		VEGF
		−/+	++	−	++	−	++
Sex
Male	45	20	25	31	14	18	27
Female	35	13	22	19	16	13	22
P		0.510		0.181		0.795
Age
≤30	33	15	18	22	11	13	20
>30	47	18	29	28	19	18	29
P		0.522		0.519		0.921
Site
Femur	28	12	16	21	7	11	17
Tibia	19	9	10	12	17	8	11
Humerus	12	5	7	6	6	6	6
Fibula	12	4	8	8	4	4	8
Radius	9	3	6	3	6	2	7
P		0.930		0.208		0.777
Stage
I	13	6	5	11	2	7	6
II	26	14	12	19	7	13	13
III	41	11	30	20	21	11	30
P		0.007		0.009^*		0.025
Recurrence or metastasis
No	43	24	19	32	11	21	22
Yes	37	9	28	18	19	10	27
P		0.004		0.018		0.046

^*Fisher’s exact test value: comparison of Campanacci stages I, II, and III. VEGF, vascular endothelial growth factor.

ISSN: 1477-7819