Scatter plot of TAFs. In (A) all TAFs obtained in this study are grouped by Dworak regression grades (study cases) or histotypes/type of invasive margin (control cases). Gray bars represent the medians within the groups. In (B) TAFs for cases DRG2 and DRG3 are plotted on a logarithmic scale. This expansion of the data overlay between groups is further appreciated. Note that assigning regression grade DRG2 to one tumor with a TAF well below the rest was due to a fairly large albeit single remaining vital tumor complex. Exp, expansive; inf, infiltrative; muc, mucinous; TAF, tumor area fractions; DRG, Dworak regression grade.