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Table 1 Merkel cell carcinoma treated with radiotherapy alone in the past 20 years in Japan

From: Complete remission of Merkel cell carcinoma on the upper lip treated with radiation monotherapy and a literature review of Japanese cases

No.

Author

Year

Age/sex

Sites

Stage

Dose

Response

Recurrence

F/U period

    

H&N

Limbs

I

II

III

IV

(Gy)

  

(months)

1

A. Aoki

1995

90F

1

    

1

40

SD

+

0

2

H. Okada

1995

83F

1

  

1

  

30

CR

+

9

3

S. Nasu

1997

88F

1

 

1

   

38

CR

 

14

4

K. Murata

1997

89F

1

  

1

  

60

CR

 

N/A

5

T. Inoue

1999

96M

1

  

1

  

50

CR

 

4

6

Y. Handa

2000

88M

 

1

1

   

51

CR

 

9

7

H. Ono

2001

78F

1

 

1

   

50

CR

 

9

8

S. Seki

2003

60M

1

  

1

  

56

CR

 

21

9

  

69F

1

  

1

  

60

CR

 

5

10

N. Narita

2004

96M

1

  

1

  

66

CR

+

1

11

E. Makino

2005

84F

1

 

1

   

48

CR

 

8

12

T. Nakamura

2005

83F

 

1

  

1

 

60

CR

+

2

13

A. Niiya

2006

72F

1

   

1

 

60

CR

+

24

14

  

66F

1

 

1

   

60

CR

 

18

15

T. Yamakawa

2008

98F

1

  

1

  

36

CR

 

12

16

R. Maeda

2010

86F

1

  

1

  

70

CR

 

19

17

J. Hujitaka

2011

87M

1

 

1

   

54

CR

 

32

18

K. Hanaoka

2011

90F

1

  

1

  

28

CR

+

4

19

A. Saito

2012

90F

1

  

1

  

45

CR

 

12

20

  

80M

1

 

1

   

60

CR

 

22

21

  

86M

 

1

 

1

  

70

CR

+

12

22

Present case

2014

75M

1

   

1

 

65

CR

 

12

 

19

3

7

11

3

1

52.6 ± 12.2

CR:21, SD:1

7/22

11.0 ± 8.4

  1. CR, complete response; F, female; F/U, follow-up; H&N, head and neck; M, male; NA, data not available; SD, stable disease.
  2. Mean age = 83.4 ± 9.9; 8 males, 14 females.