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Table 1 Merkel cell carcinoma treated with radiotherapy alone in the past 20 years in Japan

From: Complete remission of Merkel cell carcinoma on the upper lip treated with radiation monotherapy and a literature review of Japanese cases

No. Author Year Age/sex Sites Stage Dose Response Recurrence F/U period
     H&N Limbs I II III IV (Gy)    (months)
1 A. Aoki 1995 90F 1      1 40 SD + 0
2 H. Okada 1995 83F 1    1    30 CR + 9
3 S. Nasu 1997 88F 1   1     38 CR   14
4 K. Murata 1997 89F 1    1    60 CR   N/A
5 T. Inoue 1999 96M 1    1    50 CR   4
6 Y. Handa 2000 88M   1 1     51 CR   9
7 H. Ono 2001 78F 1   1     50 CR   9
8 S. Seki 2003 60M 1    1    56 CR   21
9    69F 1    1    60 CR   5
10 N. Narita 2004 96M 1    1    66 CR + 1
11 E. Makino 2005 84F 1   1     48 CR   8
12 T. Nakamura 2005 83F   1    1   60 CR + 2
13 A. Niiya 2006 72F 1     1   60 CR + 24
14    66F 1   1     60 CR   18
15 T. Yamakawa 2008 98F 1    1    36 CR   12
16 R. Maeda 2010 86F 1    1    70 CR   19
17 J. Hujitaka 2011 87M 1   1     54 CR   32
18 K. Hanaoka 2011 90F 1    1    28 CR + 4
19 A. Saito 2012 90F 1    1    45 CR   12
20    80M 1   1     60 CR   22
21    86M   1   1    70 CR + 12
22 Present case 2014 75M 1     1   65 CR   12
  19 3 7 11 3 1 52.6 ± 12.2 CR:21, SD:1 7/22 11.0 ± 8.4
  1. CR, complete response; F, female; F/U, follow-up; H&N, head and neck; M, male; NA, data not available; SD, stable disease.
  2. Mean age = 83.4 ± 9.9; 8 males, 14 females.