Table 3 Univariate analysis of survival of esophageal squamous cell carcinoma treated by curative surgery

Gender (Female)

0.939(0.535 to 1.647)

0.826

0.937(0.523 to 1.677)

0.826

Age (≥60)

0.982(0.634 to 1.519)

0.933

1.09(0.69 to 1.721)

0.712

Smoking history

1.093(0.697 to 1.717)

0.698

1.139(0.712 to 1.825)

0.587

Location

  Upper

Ref.

0.432

Ref.

0.652

  Middle

0.656(0.346 to 1.246)

0198

0.721(0.36 to 1.442)

0.355

  Lower

0.694(0.349 to 1.378)

0.296

0.771(0.368 to 1.614)

0.49

Tumor length (≥3.85 cm)

1.178(0.761 to 1.824)

0.462

1.335(0.846 to 2.106)

0.215

Differentiation

  Well

Ref.

0.2

Ref.

0.141

  Moderate

1.595(0.915 to 2.781)

0.1

1.69(0.931 to 3.067)

0.084

  Poor

1.616(0.889 to 2.939)

0.116

1.819(0.965 to 3.427)

0.064

Tumor stage

  T1

Ref.

0.011

Ref.

0.001

  T2

1.388(0.612 to 3.149)

0.432

1.591(0.605 to 4.188)

0.347

  T3

2.295(1.117 to 4.713)

0.024

3.19(1.36 to 7.481)

0.008

  T4

4.112(1.568 to 10.786)

0.004

5.968(2.058 to 17.301)

0.001

Lymph node metastasis

2.406(1.544 to 3.749)

<0.001

2.414(1.522 to 3.829)

<0.001

Pathological stages

  I

Ref.

<0.001

Ref.

<0.001

  II

1.97(0.944 to 4.113)

0.071

2.561(1.069 to 6.133)

0.035

  III

4.96(2.35 to 10.471)

<0.001

6.412(2.669 to 15.404)

<0.001

Adjuvant treatment

  None

Ref.

0.133

Ref.

0.073

  Radiotherapy

1.672(0.984 to 2.839)

0.057

1.814(1.058 to 3.111)

0.03

  Chemotherapy

0.732(0.312 to 1.714)

0.472

0.652(0.258 to 1.65)

0.367

  CRT

1.549(0.756 to 3.174)

0.232

1.521(0.712 to 3.249)

0.279

Fibrinogen level (≥4 g/L)

1.784(1.153 to 2.761)

0.009

1.992(1.259 to 3.152)

0.003

Platelet count (≥300 × 10⁹ /L)

0.918(0.524 to 1.608)

0.765

1.072(0.618 to 1.891)

0.809