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Table 3 Risk of bias in the trials included in the present meta-analysis

From: Radiofrequency ablation versus percutaneous ethanol injection for hepatocellular carcinoma: a meta-analysis of randomized controlled trials

Bias

Lencioni, 2003

Lin, 2004

Lin, 2005

Shiina, 2005

Brunello, 2008

Giorgio, 2011

Wang, 2011

Azab, 2011

Sequence generation

+

+

+

+

+

+

?

?

Allocation concealment

?

?

?

?

+

+

?

?

Double-blinding

−

−

−

−

−

−

−

−

Incomplete outcome data

−

+

−

+

−

−

−

−

Selective outcome reporting

−

−

−

−

+

−

−

−

Other sources of bias

−

+

+

−

−

−

−

+

Early stopping

?

−

−

−

+

−

−

−

Baseline imbalance

−

−

−

−

−

−

−

−

  1. +, yes; −, no; ?, unclear.