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Table 2 Distribution of c-KIT and PDGFR-α genes mutations ( N= 108)

From: Correlation between mutational status and survival and second cancer risk assessment in patients with gastrointestinal stromal tumors: a population-based study

 

c-KIT exon 11

c-KIT exon 9

PDGFR-alpha exon 12

PDGFR-alpha exon 18

Wild type

 

N

%

N

%

N

%

N

%

N

%

Site (ICD-O-3 code)

          

Stomach (C16)

31

53.5

2

25

1

50

13

100

15

55.5

Small intestine (C17)

23

39.6

6

75

0

 

0

 

11

40.7

Colon (C18)

0

 

0

 

0

 

0

 

1

3.8

Rectum (C20)

1

1.7

0

 

0

 

0

 

0

 

Peritoneum (C48.2)

3

5.2

0

 

1

50

0

 

0

 

Fletcher’s risk groups

          

LR

9

15.5

2

25

0

 

8

61.5

14

51.9

IR

13

22.4

4

50

1

50

4

30.8

7

25.9

HR

33

6.9

2

25

1

50

1

7.7

5

18.5

Met

3

5.2

0

 

0

 

0

 

1

3.7

  1. Using International Classification of Diseases for Oncology third version (ICD-O-3) and according to Fletcher et al. groups of risk. LR, low risk (includes very low risk); IR, intermediate risk; HR, high risk; Met, diagnosed in metastatic disease.