Figure 2

Histological findings in submandibular glands. (A) Severe lymphoplasmacytic infiltration with hyperplastic lymphoid follicles, so-called ‘follicular colonization’ (white arrowheads). (B) mild infiltration of IgG4-positive plasma cells (IgG4-positive/IgG-positive plasma cell ratio, 10%). (C) Monotypic predominance of kappa-light chain. (D) Infiltrating lymphocytes were positive for B cell markers (CD79a), but negative for T-cell markers (CD3).