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Table 3 Multivariate analysis of factors predicting disease-free survival in adjuvant chemotherapy with platinum-based agent

From: Cyclooxygenase-2 expression is a prognostic biomarker for non-small cell lung cancer patients treated with adjuvant platinum-based chemotherapy

 

Univariate

Multivariate

 

HR

95%CI

P value

HR

95%CI

P value

P value

      

Gender

      

  Male/female

1.25

0.49-3.18

0.639

2.11

0.77-5.82

0.149

Histology

      

  non-SQ/SQ

1.89

0.56-6.37

0.303

2.38

0.65-8.74

0.191

Pathological T factor

      

  T3-4/T1-2

1.81

0.79-4.13

0.160

1.89

0.70-5.11

0.208

Pathological N factor

      

  Positive/negative

3.63

1.34-9.85

0.011

3.15

1.12-8.85

0.030

Pleural invasion

      

  p1-3/p0

1.13

0.77-1.67

0.533

0.82

0.50-1.36

0.453

Vascular invasion

      

  Positive/negative

2.25

0.93-5.52

0.072

3.79

1.26-11.35

0.017

Cox-2 expression

      

  Positive/negative

3.14

1.16-8.49

0.024

3.96

1.38-11.38

0.011

  1. P value was calculated by log-rank test. HR: hazard ratio; 95%CI: 95% confidence interval; SQ: squamous cell carcinoma; Cox-2: cyclooxygenase-2.
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World Journal of Surgical Oncology

ISSN: 1477-7819

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