Sentinel lymph node biopsy for high-risk cutaneous squamous cell carcinoma: clinical experience and review of literature

Table 3 Cumulative results of sentinel lymph node (SLN) biopsy for high-risk cutaneous squamous cell carcinoma

	All sites	Head/Neck	Truncal/Extremity
# total cases	130	71	59
# total cases with identified SLN	128	69	59
# cases with SLN follow up	100	51	49
# cases with +SLN	18	7	11
# cases with +SLN and follow up	11	4	7
# local recurrences (LR)	5	1	4
# nodal recurrences (NR)	2	0	2
# distant recurrences (DR)	5	0	5
Rate of SLN positivity	14.1%	10.1%	18.6%
SLN failure rate*	2.2%	0%	4.8%
SLN negative predictive value	97.8%	100.0%	95.2%
SLN false negative rate†	15.4%	0%	22.2%

*defined as the percentage of recurrences in the SLN-negative biopsied nodal basins
†defined as the rate of nodal recurrences to the number of false negative and true positive SLN cases

ISSN: 1477-7819