Microvessel density and heparanase over-expression in clear cell renal cell cancer: correlations and prognostic significances

Table 1 MVD and Expression of HPA According To Clinical-pathological Parameters in ccRCC Tissues

Variables	n	%	HPA		P	MVD	P
			-	+
Total	128	100	32	96		101.64 ± 23.00
Gender
Male	82	64.1	21	61	0.832	101.39 ± 24.54	0.133
Female	46	35.9	11	35		102.07 ± 20.04
Age, Years (Median 55)
≤ 55	61	47.7	15	46	0.919	102.02 ± 20.49	0.069
> 55	67	52.3	17	50		101.27 ± 25.14
Tumor size
≤ 5 cm	83	64.8	20	63	0.748	101.93 ± 24.53	0.058
> 5 cm	45	35.2	12	33		101.11 ± 19.92
Tumor stage
T₁	50	39.1	20	30
T₂	41	32	8	33
T₃	27	21.1	3	24
T₄	10	7.8	1	9
Lymphatic metastasis
N₀	108	84.4	31	77	0.025	101.81 ± 23.84	0.056
N_1-3	20	15.6	1	19		100.72 ± 17.91
Distant metastasis
M₀	114	89.1	32	82	0.022	99.96 ± 23.66	< 0.0001
M₁	14	10.9	0	14		113.14 ± 12.88
TNM stage
I-II	76	59.4	27	49	0.001	95.96 ± 21.39	< 0.0001
III-IV	52	40.6	5	47		108.94 ± 22.94
Histologic grade
G₁-G₂	94	73.4	27	67	0.106	101.49 ± 24.02	0.238
G₃-G₄	34	26.6	5	29		102.04 ± 20.00
Venous invasion
Negative	106	82.8	26	80	0.787	101.79 ± 23.99	0.109
Positive	22	17.2	6	16		100.91 ± 17.61

ISSN: 1477-7819