Figure 4

Rectosigmoid colon recurrence from cervical cancer: (a) Preoperative patient diagnostic PET/CT scan demonstrating an ¹⁸F-FDG-avid lesion in the rectosigmoid colon (red circle). (b) Postoperative patient diagnostic PET/CT demonstrating complete removal of the ¹⁸F-FDG-avid lesion (red circle). (c) Digital photo of the WSRS (i.e., segmental rectosigmoid colon resection specimen), demonstrating the area of the rectosigmoid colon recurrence (white oval). (d) Clinical PET/CT specimen image and (e) micro PET/CT specimen image of the WSRS, demonstrating the ¹⁸F-FDG-avid lesion (red oval). (f) Digital photo depicting the first phase of the pathologic processing that produced the RDT, which consists of a single 0.5 cm slice through the rectosigmoid colon recurrence. (g) Clinical PET/CT specimen image and (h) micro PET/CT specimen image of the RDT, demonstrating the ¹⁸F-FDG-avid lesion that corresponds to the rectosigmoid colon recurrence. (i) Digital photo after sectioning of the RDT into four pieces of tissue, designated as SRDT, with two pieces containing visible tumor. (j) Clinical PET/CT specimen image and (k) micro PET/CT image of the SRDT, demonstrating ¹⁸F-FDG avidity in the two pieces that corresponds to the rectosigmoid colon recurrence. (l) H&E stained, whole-mount slide (0.4× magnification) of the specific SRDT piece that is highlighted in the red square in (i), (j), and (k), demonstrating histologic confirmation of the rectosigmoid colon recurrence of cervical cancer and the corresponding location of tumor within this specific SRDT piece. Each division of the hatched line in (c), (f), and (i) represents 1 cm.