Right lower lobe lung cancer: (a) Preoperative patient diagnostic PET/CT scan demonstrating an 18F-FDG-avid lesion in the right lower lobe (red circle). (b) Postoperative patient diagnostic PET/CT demonstrating complete removal of the 18F-FDG-avid lesion (red circle). (c) Digital photo of the WSRS (i.e. right lower lobectomy specimen), visualizing the lung cancer (red circle). (d) Clinical PET/CT specimen image of the WSRS, demonstrating the 18F-FDG-avid lesion (red circle). (e) Digital photo depicting the first phase of the pathologic processing that produced the RDT, which consists of a single 0.5 cm slice through the lung cancer. (f) Clinical PET/CT specimen image and (g) micro PET/CT specimen image of the RDT, demonstrating the 18F-FDG-avid lesion that corresponds to the lung cancer. (h) Digital photo after sectioning of the RDT into six pieces of tissue, designated as SRDT, with four pieces containing visible tumor. (i) Clinical PET/CT specimen image and (j) micro PET/CT image of the SRDT, demonstrating 18F-FDG avidity in the four pieces that corresponds to the lung cancer. (k) H&E stained, whole-mount slide (0.4× magnification) of the specific SRDT piece that is highlighted in the red rectangle in (h), (i), and (j), demonstrating histologic confirmation of the lung cancer and the corresponding location of tumor within this specific SRDT piece. Each division of the hatched line in (c), (e), and (h) represents 1 cm.