Table 1 Clinical studies evaluating blood conservation methods in major pelvic surgery and gynecologic cancer patients
Study author/year | Number of patients | operation/pathology | Methods of blood conservation |
|---|---|---|---|
Mays 1976[17] | 51 | Gyn surgery/obstet. | Iron-dextran |
Bonakdar 1982[18] | 164 | Major gyn surgery/obstet. | No transfusion |
Powell 1983[19] | 26 | Radical hysterectomy &pelvic lymphadenectomy | Nitroglycerine hypotensive anesthesia |
Takemura 1989[20] | 3 | Stage III cervical adenocarcinoma | Preoperative transcatheter arterial embolisation |
Eisencop 1990[21] | 58 | Radical hysterectomy & retroperitoneal lymph node dissection: stage IB cervical cancer | Non transfused vs transfused perioperatively |
Florica 1991[22] | 28 | Pelvic exenteration | Albumin infusion & crystalloids postoperatively |
Look 1993[23] | 97 | Squamous vulvar carcinoma | Non transfused vs transfused postoperatively |
O'Dwyer 1993[24] | 168 | Abdominal hysterectomy | Autologous blood transfusion |
Kelley 1994[25] | 8 | Extensive pelvic operations | Perioperative normovolemic hemodilution/homologous transfusion |
Monk 1995[26] | 134 | Radical hysterectomy: stage IA2-IIA cervical cancer | Non transfused vs transfused peri/postoperatively |
Connor 1995[27] | 31 | Radical hysterectomy for early cervical cancers | Intraoperative autologous blood collection & autotransfusion |
Mirhashemi 1999[42] | 50 | Radical hysterectomy type III for erly cervical cancer | Intraoperative autologous blood transfusion |
Stovall 2001[28] | Â | Gynecologic cancer patients under chemotherapy | Epoetin Alpha |
Dildy 2006[29] | 1 | hysterectomy | Pelvic pressure pack |
Massiah 2006[30] | 14 | Major gynaecological procedures | No transfusion(Jehovah's witnesses) |
Nagarsheth 2007[3] | 1 | leiomyosarcoma | Iron, folate, erythropoietin, uterine artery embolisation, recombinant VIIa, cell salvage, crystalloids |
Nagarsheth 2009[31] | 3 | Leiomyosarcoma, ovarian adenocarcinoma, pelvic mass | Blood salvage |