Table 4 Changes in biological marker status (category) between primary breast tumor and matched recurrent lesions according to DFI
Marker/DFI | Decrease | Increase | % Change | p |
|---|---|---|---|---|
primary → recurrence | value | |||
ER | ||||
DFI < 2y | + → - : 2 | - → + : 1 | 3/19 (15.8) | |
2y < DFI < 5y | + → - : 4 | - → + : 1 | 5/33 (15.2) | *p = 0.045 |
DFI > 5y | + → - : 2 | - → + : 0 | 2/45(4.4) * | DFI < 5y |
PgR | ||||
DFI < 2y | + → - : 2 | - → + : 3 | 5/19 (26.3) | |
2y < DFI < 5y | + → - : 6 | - → + : 1 | 7/33 (21.2) | NS |
DFI > 5y | + → - : 11 | - → + : 2 | 13/45 (28.9) | (0.74) |
Ki-67 Index | ||||
DFI < 2y | + → - : 0 | - → + : 5 | 5/19 (26.3) | |
2y < DFI < 5y | + → - : 2 | - → + : 6 | 8/33 (24.2) | NS |
DFI > 5y | + → - : 3 | - → + : 6 | 9/45 (20.0) | (0.83) |
p53 | ||||
DFI < 2y | + → - : 1 | - → + : 0 | 1/19 (5.3) | |
2y < DFI < 5y | + → - : 3 | - → + : 2 | 5/33 (15.2) | NS |
DFI > 5y | + → - : 1 | - → + : 5 | 6/45 (13.3) | (0.56) |
HER2 | ||||
DFI < 2y | + → - : 0 | - → + : 1 | 1/19 (5.3) | |
2y < DFI < 5y | + → - : 1 | - → + : 6 | 7/33 (21.2) | NS |
DFI > 5y | + → - : 2 | - → + : 4 | 6/45 (13.3) | (0.28) |