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Table 1 Characteristics of all patients with recurrent breast cancer in this study

From: Changes in the ER, PgR, HER2, p53 and Ki-67 biological markers between primary and recurrent breast cancer: discordance rates and prognosis

Characteristics

Number

Percent

Median age at diagnosis (years), range

53 (31 - 83)

 

Total

97

 

Tumor size at the primary tumor

  

≤ 2.0 cm

51

52.6

2.0 cm <

46

47.4

No. of positive nodes at the primary tumor

  

0

46

47.4

1-3

27

27.8

4≤

21

21.6

Unknown

3

3.1

Nuclear grade at the primary tumor

  

1

16

16.5

2

50

51.5

3

19

19.6

Unknown

12

2.1

Lymphatic invasion at the primary tumor

  

0

27

27.8

1+

51

52.6

2+

17

17.5

Unknown

2

2.1

ER at the primary tumor

  

Positive

62

63.9

Negative

35

36.1

PgR at the primary tumor

  

Positive

55

56.7

Negative

42

43.3

HER2 at the primary tumor

  

Positive

22

22.7

Negative

75

77.3

p53 at the primary tumor

  

Positive

22

22.7

Negative

75

77.3

Ki-67 index at the primary tumor

  

Positive

12

12.4

Negative

85

87.6

DFI at recurrence

  

< 2 years

19

19.6

2-5 years

33

34.0

5 years ≤

45

46.4

Sites of biopsied recurrence

  

Chest wall

39

40.2

In-breast

34

35.1

Regional lymph node

11

11.3

Lung

3

3.1

Bone

1

1.0

Brain

3

3.1

Ovary

3

3.1

Distant skin

3

3.1

Distant metastasis at biopsy

  

With

33

34.0

Without

64

66.0

Median Ki-67 value (%) at the primary tumor, range

27.0 (1-91)

 

Median DFI (months), range

57.4 (1-281)

 
  1. DFI: disease-free interval, ER: estrogen receptor, PgR: progesterone receptor