Figure 7
Effects of Ad/shBcl-xL on the expression of apoptosis or metastasis-related proteins in LoVo cells. A. Western blot detection of active caspase-9 (p47 and p37), caspase-3 (p32 and p17), PARP (p116 and p85) and uPA protein expression. B. Analysis of activity of uPA in mock LoVo or LoVo cells infected with Ad/shcontrol or Ad/shBcl-xL. The cells in 24-well plates (5.0 × 105/well) were cultured, starved in serum-free medium overnightand. Measurements were made in three separate experiments, and data are shown as mean ± standard deviation. *P < 0.05 vs mock. OD: optical density.