Figure 4

Effects of Ad/shBcl-xL on migration and invasion of LoVo cells. A. Scratch wound-healing assay. The cells were infected with mock, Ad/shcontrol or Ad/shBcl-xL as indicated. 72 h after wounding, cells with extended membrane protrusion moved into the wounded areas. Mock: no adenovirus. B. Transwell invasion assay. The invasive LoVo cells were stained and counted under microscope and quantitative results for the transmembrane ability of each group of cells (n = 3). *P < 0.05 vs mock.