Figure 2

The expression of Bcl-xL protein in CRC cells was significantly downregualted after adenovirus infection. A. Western blot analysis of Bcl-xL protein expression in mock LoVo or LoVo infected with Ad/shcontrol or Ad/shBcl-xL. B. Western blot analysis of Bcl-xL protein expression in mock LoVo or LoVo transfected with siRNA/control or siRNA/Bcl-xL. C. Western blot analysis of Bcl-2 and Mcl-1 protein expression in mock LoVo or LoVo infected with Ad/shcontrol or Ad/shBcl-xL. GAPDH was used to an internal control. Each assay was performed at least in triplicate. **P < 0.01 and *P < 0.05 vs mock.