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Table 1 Details of all cases of splenic metastases from esophageal cancer reported in literature

From: A Metachronous splenic metastases from esophageal cancer: a case report

Author Age of pt. TNM Treatment Time to onset of spleen mts Symptoms Treatment of metastases Findings Follow-up
Sanyal et al 25 pT3N1Mx Transhiatal esophagectomy 15 months Continuous, dull aching, epigastric and left hypocondrium pain radiating to back, anorexia and weight loss Splenectomy, distal pancreasectomy, splenic flexure colon resection Keratinizing squamous cell carcinoma infiltrating the pancreas After 7 months doing well
Vyas et al 63 pT3N1Mx Transhiatal esophagectomy 11 months Persistent pain and vague fullness in the left hypocondrium Systemic chemiotherapy with cisplatin and 5FU FNAB: metastatic squamous cell carcinoma Death after eleven months
Hester 65 T3N2M1 Sistemic chemiotherapy Oxaliplatin and capecitabine 9 months Left flank pain radiating to the groin and ipovolemic shock for spleen spontaneous rupture Splenic artery embolization   
Cavanna 50 T3N1M1 Systemic chemiotherapy with cisplatin and 5FU in continuous infusione (96 H) synchronous Vague discomfort in upper abdomen quadrant Sistemic chemiotherapy FNAB: metastatic squamous cell carcinoma Reduction of the spleen lesion about 50%
Kimura et al 58 T3N0M0 Transhiatal esophagectomy 6 months Vague discomfort in upper abdomen quadrant Splenic artery embolization followed by splenectomy Keratinizing squamous cell carcinoma