From: A Metachronous splenic metastases from esophageal cancer: a case report
Author | Age of pt. | TNM | Treatment | Time to onset of spleen mts | Symptoms | Treatment of metastases | Findings | Follow-up |
---|---|---|---|---|---|---|---|---|
Sanyal et al | 25 | pT3N1Mx | Transhiatal esophagectomy | 15 months | Continuous, dull aching, epigastric and left hypocondrium pain radiating to back, anorexia and weight loss | Splenectomy, distal pancreasectomy, splenic flexure colon resection | Keratinizing squamous cell carcinoma infiltrating the pancreas | After 7 months doing well |
Vyas et al | 63 | pT3N1Mx | Transhiatal esophagectomy | 11 months | Persistent pain and vague fullness in the left hypocondrium | Systemic chemiotherapy with cisplatin and 5FU | FNAB: metastatic squamous cell carcinoma | Death after eleven months |
Hester | 65 | T3N2M1 | Sistemic chemiotherapy Oxaliplatin and capecitabine | 9 months | Left flank pain radiating to the groin and ipovolemic shock for spleen spontaneous rupture | Splenic artery embolization | Â | Â |
Cavanna | 50 | T3N1M1 | Systemic chemiotherapy with cisplatin and 5FU in continuous infusione (96 H) | synchronous | Vague discomfort in upper abdomen quadrant | Sistemic chemiotherapy | FNAB: metastatic squamous cell carcinoma | Reduction of the spleen lesion about 50% |
Kimura et al | 58 | T3N0M0 | Transhiatal esophagectomy | 6 months | Vague discomfort in upper abdomen quadrant | Splenic artery embolization followed by splenectomy | Keratinizing squamous cell carcinoma | Â |