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Figure 1 | World Journal of Surgical Oncology

Figure 1

From: CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion

Figure 1

CCR9 expressed by ovarian cancer tissue. Ovarian cancer tissues from non- neoplastic (n = 8), mucinous adenocarcinoma (n = 5), serous papillary carcinoma (n = 10), and endometroid carcinoma (n = 11) were stained with isotype control or anti-CCR9 antibodies. Brown (DAB) color show CCR9 staining. An Aperio ScanScope CS system with a 40× objective captured digital images of each slide. Representative cases are indicated and immuno-intensities of CCR9 were quantified using image analysis Aperio ImageScope v.6.25 software. CCR9 expression by tissues were analyzed and presented by modified box plot. Lower, middle and upper lines, respectively, in the box represent the first quartile (Q1), Median (Q2) and third quartile (Q3). Upper (T) and lower (⊥) whiskers are represented by median ± 1.5 (Q3-Q1). Significant differences from non-neoplastic are indicated with a solid star whereas significant differences between mucinous adenocarcinoma and serous papillary as well as endometroid carcinomas are indicated with a white star in a black circle.

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