Table 4 Summary of the most frequent aberrant regions of DNA gain and loss (Tissues)
From: Genomic alterations of primary tumor and blood in invasive ductal carcinoma of breast
Chromosome | Cytoband | No. of patients (n = 30) | Frequency (%) | Chromosome | Cytoband | No. of patients (n = 30) | Frequency (%) |
|---|---|---|---|---|---|---|---|
Copy number Gain | Â | Â | Â | Â | Â | Â | Â |
1p | 1p36.33 | 12 | 12/30 (40) | 11p | 11p15.5-11p15.4 | 13 | 13/30 (43) |
1q | 1q21.2 | 12 | 12/30 (40) | 12p | 12p13.31 | 10 | 10/30 (33) |
| Â | 1q23.1 | 14 | 14/30 (47) | Â | 12p13.33 | 12 | 12/30 (40) |
| Â | 1q23.3 | 12 | 12/30 (40) | 12q | 12q21.2 | 10 | 10/30 (33) |
| Â | 1q24.3 | 12 | 12/30 (40) | 14q | 14q32.12 | 11 | 11/30 (37) |
| Â | 1q44 | 11 | 11/30 (37) | 15q | 15q11.2 | 11 | 11/30 (37) |
2p | 2p11.1 | 13 | 13/30 (43) | Â | 15q12 | 10 | 10/30 (33) |
| Â | 2p25.1 | 11 | 11/30 (37) | Â | 15q26.3 | 12 | 12/30 (40) |
3q | 3q21.1 | 12 | 12/30 (40) | 16p | 16p13.2 | 10 | 10/30 (33) |
4p | 4p16.3 | 11 | 11/30 (37) | Â | 16p13.3 | 23 | 23/30 (77) |
4q | 4q32.1 | 10 | 10/30 (33) | 16q | 16q22.1 | 11 | 11/30 (37) |
| Â | 4q35.2 | 10 | 10/30 (33) | 17p | 17p13.3 | 10 | 10/30 (33) |
5p | 5p15.33 | 24 | 24/30 (80) | 17q | 17q11.2 | 19 | 19/30 (63) |
7p | 7p14.1 | 10 | 10/30 (33) | Â | 17q12 | 11 | 11/30 (37) |
8q | 8q11.1 | 12 | 12/30 (40) | Â | 17q21.1 | 11 | 11/30 (37) |
| Â | 8q11.21 | 10 | 10/30 (33) | Â | 17q25.3 | 18 | 17/30 (57) |
| Â | 8q21.3 | 13 | 13/30 (43) | 18q | 18q23 | 15 | 15/30 (50) |
| Â | 8q22.2 | 17 | 17/30 (57) | 19p | 19p13.3 | 13 | 13/30 (43) |
| Â | 8q24.3 | 23 | 23/30 (77) | 19q | 19q13.43 | 10 | 10/30 (33) |
10p | 10p15.3 | 10 | 10/30 (33) | 20q | 20q13.33 | 21 | 21/30 (70) |
10q | 10q26.3 | 15 | 15/30 (50) | 21q | 21q11.2 | 11 | 11/30 (37) |
11p | 11p15.4 | 10 | 10/30 (33) | 22q | 22q13.33 | 15 | 15/30 (50) |
| Â | 11p15.5 | 14 | 14/30 (47) | Xp | Xp11.23 | 10 | 10/30 (33) |
Copy number Loss | Â | Â | Â | Â | Â | Â | Â |
3p | 3p21.31 | 5 | 5/30 (17) | 16q | 16q23.1 | 4 | 4/30 (13) |
4q | 4q35.2 | 6 | 6/30 (20) | 17p | 17p11.2 | 12 | 12/30 (40) |
6p | 6p25.3 | 5 | 5/30 (17) | 22q | 22q11.1 | 5 | 5/30 (17) |
7q | 7q22.1 | 6 | 6/30 (20) | Â | 22q11.21 | 11 | 11/30 (37) |
14q | 14q32.33 | 8 | 8/30 (27) | Â | 22q11.23 | 7 | 7/30 (23) |
16q | 16q22.3 | 4 | 4/30 (13) | Â | Â | Â | Â |