Table 3 Summary of the most frequent aberrant regions of DNA gain and loss (Blood)
From: Genomic alterations of primary tumor and blood in invasive ductal carcinoma of breast
Chromosome | Cytoband | No.of patients (n = 30) | Frequency (%) | Chromosome | Cytoband | No. of patients (n = 30) | Frequency (%) |
|---|---|---|---|---|---|---|---|
Copy number Gain | Â | Â | Â | Â | Â | Â | Â |
1p | 1p36.12 | 13 | 13/30 (43) | 12q | 12q21.2 | 10 | 10/30 (33) |
| Â | 1p36.13 | 12 | 12/30 (40) | 14q | 14q32.12 | 13 | 13/30 (43) |
| Â | 1p36.31 | 10 | 10/30 (33) | 15q | 15q11.2 | 11 | 11/30 (37) |
| Â | 1p35.1 | 13 | 13/30 (43) | Â | 15q12 | 10 | 10/30 (33) |
1q | 1q23.1 | 11 | 11/30 (37) | Â | 15q25.2 | 10 | 10/30 (33) |
2p | 2p11.2 | 11 | 11/30 (37) | 16p | 16p11.2 | 11 | 11/30 (37) |
| Â | 2p13.1 | 14 | 14/30 (47) | Â | 16p13.3 | 16 | 16/30 (53) |
3p | 3p22.1 | 10 | 10/30 (33) | 16q | 16q22.1 | 12 | 12/30 (40) |
| Â | 3p22.2 | 11 | 11/30 (37) | Â | 16q24.1 | 13 | 13/30 (43) |
3q | 3q21.1 | 12 | 12/30 (40) | Â | 16q24.3 | 11 | 11/30 (37) |
| Â | 3q21.3 | 15 | 15/30 (50) | 17p | 17p11.2 | 13 | 13/30 (43) |
| Â | 3q27.1 | 10 | 10/30 (33) | Â | 17p12 | 11 | 11/30 (37) |
4p | 4p16.3 | 15 | 15/30 (50) | Â | 17p13.2 | 10 | 10/30 (33) |
5p | 5p13.3 | 12 | 12/30 (40) | Â | 17p13.3 | 14 | 14/30 (47) |
| Â | 5p15.33 | 17 | 17/30 (57) | 17q | 17q11.2 | 17 | 17/30 (57) |
5q | 5q33.1 | 12 | 12/30 (40) | Â | 17q12 | 13 | 13/30 (43) |
7q | 7q11.23 | 12 | 12/30 (40) | Â | 17q21.1 | 10 | 10/30 (33) |
| Â | 7q36.3 | 10 | 10/30 (33) | Â | 17q21.2 | 11 | 11/30 (37) |
8p | 8p21.2 | 11 | 11/30 (37) | Â | 17q21.32 | 13 | 13/30 (43) |
8q | 8q24.3 | 20 | 20/30 (67) | Â | 17q25.3 | 18 | 18/30 (60) |
9p | 9p12 | 11 | 11/30 (37) | 18q | 18q23 | 10 | 10/30 (33) |
9q | 9q34.11-9q34.12 | 17 | 17/30 (57) | 19p | 19p13.11 | 15 | 15/30 (50) |
10p | 10p15.3 | 11 | 11/30 (37) | Â | 19p13.3 | 16 | 16/30 (53) |
10q | 10q22.3 | 11 | 11/30 (37) | 19q | 19q13.2 | 11 | 11/30 (37) |
| Â | 10q26.3 | 11 | 11/30 (37) | Â | 19q13.33 | 11 | 11/30 (37) |
11p | 11p11.2 | 12 | 12/30 (40) | Â | 19q13.43 | 11 | 11/30 (37) |
| Â | 11p15.4 | 12 | 12/30 (40) | 20p | 20p12.2 | 10 | 10/30 (33) |
| Â | 11p15.5 | 18 | 18/30 (60) | 20q | 20q13.12 | 10 | 10/30 (33) |
| Â | 11p15.5-11p15.4 | 12 | 12/30 (40) | Â | 20q13.33 | 16 | 16/30 (53) |
11q | 11q12.3 | 13 | 13/30 (43) | 22q | 22q12.2 | 19 | 19/30 (63) |
| Â | 11q23.1 | 10 | 10/30 (33) | Â | 22q13.31 | 15 | 15/30 (50) |
| Â | 11q23.3 | 11 | 11/30 (37) | Â | 22q13.33 | 15 | 15/30 (50) |
12p | 12p13.31 | 18 | 18/30 (60) | Xp | Xp11.22 | 14 | 14/30 (47) |
| Â | 12p13.33 | 12 | 12/30 (40) | Â | Xp11.23 | 10 | 10/30 (33) |
12q | 12q13.13 | 10 | 10/30 (33) | Xq | Xq23 | 11 | 11/30 (37) |
Copy number Loss | Â | Â | Â | Â | Â | Â | Â |
1q | 1q44 | 5 | 5/30 (17) | 11q | 11q25 | 6 | 6/30 (20) |
2p | 2p25.3 | 5 | 5/30 (17) | 13q | 13q34 | 6 | 6/30 (20) |
2q | 2q37.3 | 7 | 7/30 (23) | 14q | 14q32.33 | 8 | 8/30 (27) |
3p | 3p26.3 | 5 | 5/30 (17) | 16q | 16q21 | 5 | 5/30 (17) |
5q | 5q13.2 | 6 | 6/30 (20) | 18p | 18p11.32 | 8 | 8/30 (27) |
6p | 6p25.3 | 6 | 6/30 (20) | 21q | 21q21.1 | 5 | 5/30 (17) |
7q | 7q22.1 | 6 | 6/30 (20) | 22q | 22q11.1 | 7 | 7/30 (23) |
10q | 10q11.22 | 8 | 8/30 (27) | Â | 22q11.21 | 14 | 14/30 (47) |