Table 2 Prognostic factors in Marjolin's ulcers [19-24]
From: Marjolin's ulcers: theories, prognostic factors and their peculiarities in spina bifida patients
| Â | Â | PROGNOSIS | |
|---|---|---|---|
| Â | Variable | Better | Poorer |
Clinical | Latency to malignancy | Less than 5 years | More than 5 years |
| Â | Tumor location | Head, neck, upper extremeties | Lower limbs, trunk |
| Â | Tumor source | Post-burn, chronic osteomyelitis | Pressure sore carcinomas |
| Â | Tumor diameter | Smaller than 2 cm | 2 cm or more |
| Â | Tumor type | Exophytic | Infiltrative |
| Â | Metastases | None | Present |
| Â | Tumor recurrence | None | Present |
Histological | Degree of differentiation | Well differentiated | Moderately-well and poorly differentiated |
| Â | Peritumoral T lymphocyte infiltration | Heavy | Scarce or absent |
| Â | Depth of dermal invasion | Superficial to reticular dermis | Reticular dermis or deeper |
| Â | Vertical tumor thickness | Less than 4 mm thick | 4 mm thick or more |