Figure 6
From: Expression of cell cycle proteins in male breast carcinoma
Schematic illustration of the regulatory proteins in the cell cycle phases. The cell cycle is illustrated (outer blue circle) schematically through its various phases--G1/S, G2/M. (G1 = growth phase 1; S = synthesis; G2 = growth phase 2; M = mitosis). The proteins studied are color coded to the most prominent phase of their action in the cell cycle: Cyclin D1 is green, G1. p21, p27, p57 are orange, S/G2. p16 is violet, G1. Ki67 (coral) and PCNA (brown) all phases. P53 is black, checkpoint G2/M. The insert are two photomicrographs of the immunohistochemical expression of p27 and p16 in the malignant breast cancer cells at a medium magnification ×150.