Figure 3
The macroscopic appearance of the transected specimen (A) reveals a cystic dilatation of the intrahepatic bile ducts with intraluminal mucin and multiple papillary tumors. Arrows indicate a poorly differentiated carcinoma with neuroendocrine differentiation abutting on the main tumor. Histopathological examination (B) demonstrates papillary structures without stromal invasion (hematoxylin and eosin ×40). This oncocytic type papillary cholangiocarcinoma (C) shows a columnar lining with abundant oxyphilic granular cytoplasm with intraepithelial lumina, which gives rise to a cribriform pattern of growth (hematoxylin and eosin ×200).