Table 5 Events after 1^st treatment (based on dose received)

50 mg dose

N = 3

Nausea

1

33.3

Vomiting

1

33.3

Hypertension

1

33.3

Liver Dysfunction

1

33.3

100 mg dose

N = 45

Nausea

2

4.4

Vomiting

1

2.2

Gastritis

1

2.2

Pain

1

2.2

Liver Dysfunction

1

2.2

150 mg dose

N = 1

Nausea

1

100

Vomiting

1

100

Anorexia

1

100

200 mg dose

N = 6

Liver dysfunction

1

16.7