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Table 2 Distribution of Grade III-IV Toxicity based on Site of Disease

From: Intra-arterial chemoradiation for T3-4 oral cavity cancer: Treatment outcomes in comparison to oropharyngeal and hypopharyngeal carcinoma

Toxicity grade III & IV

Oral Cavity (n = 22)

Oropharynx (n = 94)

Hypopharynx (n = 39)

Total (n = 155)

Mucositis

8 (36%)

34 (36%)

7 (18%)

49 (31%)

Hematologic

4 (18%)

11 (12%)

2 (5%)

17 (11%)

Neurologic

0

7 (7.5%)

1 (2.5%)

8 (5%)

Gastrointestinal

0

4 (4%)

0

4 (2.5%)

Cardiac

0

5 (5%)

0

4 (2.5%)

Circulatory

0

1 (1%)

0

1 (0.06%)

Ototoxicity

0

0

1 (2.5%)

1 (0.06%)

Total Events

12

62

11

85

No. of patients

11 (50%)

54 (57%)

10 (26%)

75 (48%)

  1. 10 patients had more than one episode of grade III-IV toxicity resulting in a total of 85 events among 75 patients.