10 mm, lymph-vascular space involvement, tumor diameter > 17.5 mm, and parametrial involvement. Postoperative treatment was significantly more frequent in patients with "abundant" vascularization (OR: 20.8, 95% CIs: 2 to 211). The presence of scanty-moderate vascularization with a PI < 0.82 or abundant vascularization with either PI > 0.82 or PI < 0.82 was associated with high-risk group in 94.4% of the cases (OR: 21.2, 95% CI: 1.9 to 236.0) Conclusion The results are consistent with a relationship between tumor angiogenesis and prognostic factors for recurrence in early cervical cancer. "Abundant" vascularization and PI < 0.82 may be related to postoperative treatment due to risk factors."/>
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Table 3 Pulsatility index and prognostic factors

From: Neoangiogenesis in early cervical cancer: Correlation between color Doppler findings and risk factors. A prospective observational study

  Lowest PI* P value
PLN   0.473
   Negative 0.89 (0.68 – 1.10)  
   Positive 0.74 (0.52 – 0.95)  
DSI   0.004
   < 10 mm 1.20 (0.91 – 1.60)  
   > 10 mm 0.74 (0.55 – 0.92)  
LVSI   0.073
   Negative 1.00 (0.75 – 1.30)  
   Positive 0.68 (0.44 – 0.92)  
Tumor size   0.158
   < 17.5 mm 1.06 (0.68 – 1.40)  
   > 17.5 mm 0.80 (0.60 – 1.40)  
Parametrium   0.171
   Negative 0.95 (0.73 – 1.17)  
   Positive 0.67 (0.48 – 0.86)  
Histology   0.406
   SCC 0.84 (0.63 – 1.05)  
   Non-SCC 0.99 (0.61 – 1.37)  
  1. * Expressed as median, range in parentheses.
  2. SCC = Squamous cell carcinoma. PLN = Pelvic Lymph node. DSI = Depth stromal invasion. LVSI = Lymph-vascualr space invasion.
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World Journal of Surgical Oncology

ISSN: 1477-7819

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