Table 2 Immunohistochemistry and Mutations in the primary omental GISTs
Case No. | Histology | Immunohistochemistry | Mutations | |||||
|---|---|---|---|---|---|---|---|---|
KIT | CD34 | S100 | SMA | Desmin | Gene | Site | ||
15 | Spindle | Positive | + | - | - | - | C-kit | Exon11, MS |
16 | Spindle | Positive | + | - | - | - | C-kit | Exon11, IFD |
17 | Spindle | Positive | + | - | - | - | C-kit | Exon11, MS |
18 | Spindle | Positive | + | - | - | - | C-kit | Exon11, MS |
19 | Spindle | Positive | + | - | Weak | - | C-kit | Exon11, IFD |
22 | Myxoid epithelioid | Weak | + | - | + | - | PDGFRA | Exon18 del D842V |
23 | Epithelioid | Weak | - | - | - | - | PDGFRA | Exon18 DIMH842-845 |
26 | Epithelioid | Weak | + | NA | NA | NA | PDGFRA | Exon18 |
28 | Myxoid epithelioid | Weak | + | - | - | - | PDGFRA | Exon12, V561D |