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Table 1 Pathological complete response rates in trials of preoperative radiation or chemoradiation with and without brachytherapy.

From: Radiation-sparing managements for cervical cancer: a developing countries perspective

# of pat [ref] EBRT+BT EBRT/CT+BT EBRT/CT no BT path CR (%)
66 [55] 37.4-40Gy+20Gy    69
61 [56] 46Gy CDDP+27Gy    44
360 [57] 20Gy+40Gy    48
168 [58] 45Gy+30Gy    41
123 [51] 45Gy+30Gy    48
      Mean (50.0%)
20 [59]   45Gy CDDP/5FU+20Gy   60
43 [57]   45Gy CDDP+15Gy   63
35 [60]   45Gy CDDP/5FU+20Gy   45
175 [58]   45Gy CDDP+30Gy   52
112 [61]   45Gy CDDP/FU+15Gy   49
175 [62]   44Gy CDDD+16Gy   38
      Mean (51.1%)
30 [63]    45Gy CDDP/5FU 46.6
100 [64]    39Gy CDDP/5FU 45.2
24 [53]    39Gy CDDP/5FU 54.2
40 [70]    50Gy CDDP 45
40 [70]    50Gy CDDP/GEM 67
      Mean (51.6%)
  1. Most patients were IB2-IIA, some included IIB. Trials whose definition of complete pathological response encompased microscopic residual disease were not accounted.