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World Journal of Surgical Oncology
Table 1 Four different studies showing that between 40% to 70% of previously untreated NPC specimens have loss of p16 expression.
Cyclin D1 and p16 expression in recurrent nasopharyngeal carcinoma
Number of NPC specimens examined
Percent of NPC with loss of p16 staining
Hwang et al 
Makitie et al 
Huang et al 
Baba et al 
Lin et al [this study]
This is in contrast to the 96% of recurrent NPC found in this study to have loss of p16 expression.
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