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Table 1 Four different studies showing that between 40% to 70% of previously untreated NPC specimens have loss of p16 expression.

From: Cyclin D1 and p16 expression in recurrent nasopharyngeal carcinoma

Investigators Number of NPC specimens examined Percent of NPC with loss of p16 staining
Hwang et al [13] 65 65%
Makitie et al [16] 84 70%
Huang et al [15] 74 42%
Baba et al [14] 20 40%
Lin et al [this study] 27 96%
  1. This is in contrast to the 96% of recurrent NPC found in this study to have loss of p16 expression.