Year of diagnostic | |||||||
---|---|---|---|---|---|---|---|
Before 1990 (n = 207) | 1990 and after (n = 219) | ||||||
n | x OS (m) | 5-y OS (%) | n | x OS (m) | 5-y OS (%) | ρ | |
Gender | |||||||
Male | 135 | 26 | 32 | 141 | 120+ | 58 | < .0001 |
Female | 72 | 113 | 53 | 78 | 120+ | 69 | = .0434 |
Age, years | |||||||
< 61 | 112 | 34 | 42 | 69 | 120+ | 57 | = .0504 |
> 61 | 95 | 31 | 37 | 149 | 120+ | 64 | < .0001 |
Tumor location | |||||||
Cardia | 10 | 36 | 26 | 22 | 120+ | 90 | = .0021 |
Body | 59 | 33 | 38 | 69 | 120+ | 62 | = .0022 |
Antrum | 89 | 38 | 44 | 98 | 120+ | 59 | = .0253 |
Lymph node involvement | |||||||
N0 | 85 | 216+ | 62 | 96 | 120+ | 73 | = .0328 |
N+ | 122 | 22 | 23 | 123 | 120+ | 52 | < .0001 |
Stage | |||||||
I | 33 | 204+ | 81 | 59 | 120+ | 81 | = .6689 |
II | 65 | 78 | 51 | 51 | 120+ | 70 | = .0132 |
IIIA | 64 | 23 | 23 | 54 | 120+ | 57 | = .0008 |
IIIB | 44 | 19 | 15 | 39 | 23 | 30 | = .2315 |
Lymphadenectomy | |||||||
D1 | 184 | 31 | 39 | 65 | 26 | 26 | = .6718 |
D2 | 22 | 52 | 42 | 123 | 120 | 66 | = .0076 |
Adjuvant Chemotherapy | |||||||
No | 98 | 22 | 30 | 94 | 60 | 45 | = .006 |
Yes | 109 | 58 | 48 | 126 | 120+ | 73 | = .0003 |
Chemotherapy | |||||||
MMC | 89 | 48 | 47 | 44 | 120+ | 58 | = .2346 |
MMC-TG | 20 | 80 | 54 | 82 | 120+ | 87 | = .0113 |