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Table 1 Histologic classification and "aberrant" E-cadherin staining patterns in invasive mammary carcinomas.

From: Aberrant E-cadherin staining patterns in invasive mammary carcinoma

Case

In-situ

E-cadherin

Invasive

E-cadherin

Metastasis

E-cadherin

1

Lobular

Negative

Ductal

Negative

Lobular

Negative

2

Ductal

Pos, ++

Ductal

Pos, +

Lobular

Pos, +++

 

Lobular

Negative

    

3

Lobular

Negative

Ductal

Pos, +

CK-pos

Not Done

   

Ductal

Negative

  

4

Lobular

Not Done

Lobular

Pos, +++*

Lobular

Pos, +++

5

Lobular

Negative

Lobular

Negative

None

 
  1. *in pleomorphic areas. Weak, discontinuous positivity was seen in more classical areas of invasive carcinoma in the same tumor.
  2. Pos-positive; + weak, ++ moderate, and +++ strong cell membrane immunoreactivity.
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World Journal of Surgical Oncology

ISSN: 1477-7819

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