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Table 2 Profiles of the cases of primary small-cell neuroendocrine carcinoma in the duodenum reported in the literature.

From: Primary small-cell neuroendocrine carcinoma of the duodenum – a case report and review of literature

 

Author Year

Age/sex

Clinical Manifestations

Size (mm)

Morphology

Location

Metastasis

Surgery

Chemotherapy

Prognosis (month)

1

Swanson 1986 [7]

76 M

Abdominal pain, anorexia, weight loss

15

ulceration

adjacent to the ampulla*

LN, liver

biospy

5-FU, doxorubicin, mitomycin

Dead (1.5)

2

Zamboni 1990 [8]

62 M

jaundice, weight loss

25

polypoid

the papilla of Vater

LN

PD

-

Dead (7)

3

Zamboni 1990 [8]

66 M

jaundice, abdominal pain

20

ulceration

the papilla of Vater

LN

PD

-

Dead (6)

4

Zamboni 1990 [8]

51 M

jaundice, weight loss, abdominal pain

30

soft fungating mass

the papilla of Vater

LN

PD

-

Dead (17)

5

Lee 1992 [9]

86 M

jaundice, recurrent pancreatitis

?

polypoid

Peri ampullary

?

-

-

(>5)

6

Sarker 1992 [10]

53 F

jaundice, weight loss, back pain

35

mass with small ulceration

the papilla of Vater

LN

PD

5-FU, TNF, interferon

Recurrence + (>18)

7

Sato 1995 [11]

74 M

jaundice

35

polypoid

the papilla of Vater

?

PPPD

-

?

8

Shim 2000 [12]

54 M

jaundice

30

ulceration

the papilla of Vater

liver

PD

cisplatin, etoposide, radiation

Dead (8)

9

Sata 2004 present case

57 M

GI Tract bleeding

30

mass with ulceration

Peri ampullary

-

Local resection

5-FU leucovorin

disease free (>48)

  1. * Hormone VIP; ? Don't know; M – male; F – Female; PD-pancreaticoduodenectomy; LN-lymph node; PPPD-pylorus preserving pancreaticoduodenectomy; 5 FU-f fluoro uracil; TNF – tumor necrosis factor