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Table 3 CDH1 three-marker haplotype analysis in diffuse gastric cancer cases

From: CDH1 polymorphisms and haplotypes in sporadic diffuse and intestinal gastric cancer: a case–control study based on direct sequencing analysis

Three polymorphisms Haplotype Cases (%) Controls (%) OR Lower 95% CI Upper 95% CI P-value
−160C → A CTT 24.70 25 1.132 0.860 1.489 0.011
48 + 6 T → C ATT 5.93 4.48 1.511 0.926 2.466  
2076C → T CCC 12.07 13.27 1.030 0.731 1.452  
  CTC 31.78 36.38 1    
  CCT 3.80 4.48 0.954 0.552 1.648  
  ATC 18.81 15.11 1.431 1.051 1.949  
  ACC 2.52 0.93 3.272 1.322 8.096  
  ACT 0.38 0.37 0.954 0.158 5.761  
−160C → A CTT 7.72 8.02 1.079 0.729 1.597 0.042
1937-13 T → C ATT 1.41 0.75 2.073 0.732 5.872  
2253C → T CCC 3.20 3.36 1.075 0.599 1.929  
  CTC 61.22 67.53 1    
  CCT 0.21 0.19 0.691 0.062 7.648  
  ATC 23.34 18.47 1.4 1.078 1.819  
  ACC 2.86 16.79 0.184 0.111 0.306  
  ACT 0.04 0  
−160C → A CCT 1.62 14.93 0.108 0.055 0.212 0.096
2076C → T ACT 0.09 0.19 0.691 0.058 7.227  
2253C → T CTC 37.54 42.91 0.909 0.703 1.176  
  CCC 26.88 27.99 1    
  CTT 6.31 6.72 0.987 0.628 1.551  
  ACC 6.23 4.66 1.406 0.862 2.293  
  ATC 19.97 15.49 1.332 0.971 1.827  
  ATT 1.37 0.56 2.341 0.771 7.111  
−160C → A CTC 53.84 58.79 0.904 0.470 1.739 0.103
48 + 6 T → C ATC 22.01 17.91 1.21 0.613 2.389  
1937-13 T → C CCT 0.77 0.93 0.882 0.237 3.281  
  CTT 2.65 2.61 1    
  CCC 15.10 16.79 0.888 0.445 1.772  
  ATT 2.73 1.68 1.588 0.616 4.094  
  ACT 0.17 0  
  ACC 2.73 1.31 2.021 0.754 5.416