Table 1 Clinical characteristics of the 61 patients with testicular yolk sac tumor
From: Testicular yolk sac tumors in children: a review of 61 patients over 19 years
Case no. | Age (months) | Tumor | Pre-AFP (ng/mL) | Surgery | CTX | Follow-up (months) | AFP (ng/mL) (follow-up) | Surgery (follow-up) | CTX (follow-up) | Biopsy (follow-up) | Outcome (48 month average) | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 6 | YST | 1,020 | HIO | VCR + KSM | 1 | 32.4 | - | CBP + VP-16 | NED | ||
2 | 17 | YST | 6,160 | HIO | PEB | 4 | 2.3-10.2 | - | PEB | NED | ||
3 | 25 | YST | >363 | HIO | PEB | 7 | 1.8-16.9 | - | PEB | NED | ||
4 | 15 | YST | >363 | HIO | PEB | 3 | 1.5-38.3 | - | PEB | NED | ||
5 | 45 | YST | 151 | HIO | PEB | 3 | 1.7-3.7 | - | PEB | NED | ||
6 | 6 | YST | 990 | HIO | PEB | 6 | 2.53-8.5 | - | PEB + PVB | NED | ||
7 | 20 | YST | >363 | HIO | PEB | 2 | 2.6-8.4 | - | PEB + PVB | NED | ||
8 | 24 | YST | 102 | HIO | PEB | 5 | 2.3-3.2 | - | PEB + PVB | NED | ||
9 | 18 | YST | 91.6 | HIO | PEB | 2 | 2.9-4.31 | - | PEB + PVB | NED | ||
10 | 23 | YST | 14,900 | HIO | PEB | 2 | 1.8-17.5 | - | PEB | NED | ||
11 | 23 | YST | >363 | HIO | PEB | 2 | 8.65-40.2 | - | PEB + PVB | NED | ||
12 | 15 | YST | >363 | HIO | PEB | 2 | 1.88-5.05 | - | PEB + PVB | NED | ||
13 | 7 | YST | >363 | HIO | PEB | 2 | 9.6-24.8 | - | PEB | NED | ||
14 | 13 | YST | >363 | HIO | PEB | 2 | Unknown | - | PEB | NED | ||
15 | 21 | YST | Unknown | HIO | Unknown | 2 | 1.78-5.49 | - | PEB + PVB | NED | ||
16 | 21 | YST | >363 | HIO | PEB | 3 | 4.2-15.5 | - | PEB + PVB | NED | ||
17 | 12 | YST | >363 | HIO | PEB | 2 | 19.7-63.5 | - | PEB + PVB | NED | ||
18 | 54 | YST | >363 | HIO | PEB | 2 | 3.3-169 | - | PEB | NED | ||
19 | 39 | YST | >363 | HIO | PEB | 2 | 2.7 | - | PEB | NED | ||
20 | 50 | YST | 20.9 | HIO | PEB | 2 | 2.44-3.71 | - | PEB | NED | ||
21 | 12 | YST | >363 | HIO | PEB | 2 | 23.1-4.4 | - | PEB | NED | ||
22 | 10 | YST | >363 | HIO | PEB | 2 | 5.84-19.1 | - | PEB | NED | ||
23 | 41 | YST | >363 | HIO | PEB | 2 | 2.12-7.2 | - | PEB | NED | ||
24 | 13 | YST | >363 | HIO | PEB | 2 | 3.78-32.4 | - | PEB | NED | ||
25 | 1 | YST | >363 | HIO | PEB | 1 | 6.85 | - | PEB | NED | ||
26 | 25 | YST | 142 | HIO | PEB | 2 | 2.76-5.35 | - | PEB | NED | ||
27 | 10 | YST | >363 | HIO | PEB | 1 | 2.52 | - | PEB | NED | ||
28 | 15 | YST | HIO | Unknown | 3 | 3.34-23.1 | - | CBP + VCR + BLM | NED | |||
Relapse | 29 | 21 | YST | >363 | HIO | PEB | 2 | 3.75-11.9 | Plan A excision + hernia sac high ligation | PEB | Match | NED |
30 | 14 | YST | 9,092.5 | HIO | VCR + KSM | 9th month | >400 | Plan B | CBP + VCR + KSM | Match | NED | |
10th month | Normal | VCR + KSM | NED | |||||||||
31 | 23 | YST | 284 | HIO | VCR | 3rd month | 909 | Plan B | VCR + KSM + DDP | Match | NED | |
Stage II | 32 | 23 | YST | Unknown | TSS | VCR | - | Abandon | Unkown | |||
33 | 30 | YST | Unknown | HIO | Unknown (outer court) | 5th month | >4,000 | - | Abandon | Unkown | ||
34-61 | Lost to follow-up after the surgery | |||||||||||