Table 2 Univariate and multivariate analyses of factors associated with survival in gastric cancer patients with neoadjuvant chemotherapy
Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |
CA19-9 | ||||
Positive versusnegative | 2.198 (1.459-3.311) | 0.000 | 2.183 (1.085-4.392) | 0.029 |
CA72-4 | ||||
Positive versusnegative | 1.887 (1.241-2.869) | 0.003 | 2.500 (1.269-4.926) | 0.008 |
Vascular invasion | ||||
Positive versus negative | 2.401 (1.616-3.567) | 0.000 | 1.564 (0.817-2.995) | 0.177 |
TNM (pathological) | ||||
III + IV versusI + II | 6.041 (3.295-11.074) | 0.000 | 5.066 (1.887-13.599) | 0.001 |
Recurrence | ||||
Positive versusnegative | 1.745 (1.161-2.625) | 0.007 | 0.755 (0.337-1.693) | 0.495 |
Clinical response to NCT | ||||
PD versus DC | 2.474 (1.274-4.802) | 0.007 | 1.103 (0.404-3.013) | 0.849 |
Pathologic response to NCT | ||||
pCR + pPR versus pNR | 0.419 (0.218-0.805) | 0.009 | 0.739 (0.322-1.696) | 0.475 |