Figure 4
Therapeutic effect of irradiation combined with IGF-1r siRNA in vivo . The survival fraction after treatment is shown for (A) Eca-109 and (B) TE-1 cells, respectively. Irradiation alone enhanced tumor growth inhibition and led to shorter survival times than the combination treatment. The tumor volume was calculated at the indicated times in the (C) Eca-109 and (D) TE-1 cell groups, respectively. The statistical significance of the tumor volume changes was calculated using Student’s t-test.