From: Prognostic value of poorly differentiated clusters in invasive breast cancer
Variable | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
Hazard ratio | 95% confidence interval | P | Hazard ratio | 95% confidence interval | P | |
Age 40 or younger/>40 | 0.410 | 0.193 to 0.869 | 0.020* | 0.622 | 0.279 to 1.388 | 0.246 |
T stage: T1/T2/T3 | 2.956 | 1.513 to 5.775 | 0.002* | 4.064 | 1.839 to 8.982 | 0.001* |
N stage: N0/N1/N2 or 3 | 2.890 | 1.848 to 4.519 | <0.001* | 3.482 | 1.185 to 10.234 | 0.023* |
Lymphovascular invasion: negative/positive | 3.841 | 1.909 to 7.729 | <0.001* | 0.516 | 0.106 to 2.507 | 0.412 |
Grade: G1/G2/G3 | 1.698 | 0.880 to 3.276 | 0.114 | Not assessed | ||
Estrogen receptor or progesterone receptor: negative/positive | 0.922 | 0.460 to 1.849 | 0.819 | Not assessed | ||
HER-2: negative/positive | 2.577 | 1.172 to 5.668 | 0.019* | 0.874 | 0.357 to 2.136 | 0.767 |
Triple negative status: no/yes | 1.393 | 0.670 to 2.895 | 0.375 | Not assessed | ||
Poorly differentiate cluster grade: G1/G2/G3 | 4.987 | 2.681 to 9.276 | <0.001* | 3.730 | 1.718 to 8.101 | 0.001* |
Tumor budding: G1/G2/G3 | 2.285 | 1.442 to 3.623 | <0.001* | 1.517 | 0.597 to 2.564 | 0.120 |