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Table 4 Overall survival analysis by the Cox proportional hazards regression model in 146 cases of IDC-NOS

From: Prognostic value of poorly differentiated clusters in invasive breast cancer

    Variable Univariate Multivariate
Hazard ratio 95% confidence interval P Hazard ratio 95% confidence interval P
Age 40 or younger/>40 0.410 0.193 to 0.869 0.020* 0.622 0.279 to 1.388 0.246
T stage: T1/T2/T3 2.956 1.513 to 5.775 0.002* 4.064 1.839 to 8.982 0.001*
N stage: N0/N1/N2 or 3 2.890 1.848 to 4.519 <0.001* 3.482 1.185 to 10.234 0.023*
Lymphovascular invasion: negative/positive 3.841 1.909 to 7.729 <0.001* 0.516 0.106 to 2.507 0.412
Grade: G1/G2/G3 1.698 0.880 to 3.276 0.114    Not assessed
Estrogen receptor or progesterone receptor: negative/positive 0.922 0.460 to 1.849 0.819    Not assessed
HER-2: negative/positive 2.577 1.172 to 5.668 0.019* 0.874 0.357 to 2.136 0.767
Triple negative status: no/yes 1.393 0.670 to 2.895 0.375    Not assessed
Poorly differentiate cluster grade: G1/G2/G3 4.987 2.681 to 9.276 <0.001* 3.730 1.718 to 8.101 0.001*
Tumor budding: G1/G2/G3 2.285 1.442 to 3.623 <0.001* 1.517 0.597 to 2.564 0.120
  1. *P <0.05.