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Table 2 Correlation between poorly differentiated clusters and other clinicopathological characteristics

From: Prognostic value of poorly differentiated clusters in invasive breast cancer

     Variable Poorly differentiated clusters P
G1 (%) G2 (%) G3 (%)
Age     
40 or younger 3 (7.3%) 11 (18.3%) 11 (24.4%) 0.103
>40 38 (92.7%) 49 (81.7%) 34 (75.6%)  
T stage     
T1 8 (19.5%) 10 (16.7%) 6 (13.3%) 0.779
T2 30 (73.2%) 43 (71.7%) 32 (71.1%)  
T3 3 (7.3%) 7 (11.6%) 7 (15.6%)  
N stage     
N0 30 (73.2%) 29 (78.3%) 11 (24.4%) <0.001*
N1 8 (19.5%) 20 (33.3%) 16 (35.6%)  
N2 or 3 3 (7.3%) 11 (18.3%) 18 (40.0%)  
Grade     
G1 3 (7.3%) 4 (6.7%) 0 (0.0%) 0.134
G2 25 (61.0%) 42 (70.0%) 35 (77.8%)  
G3 13 (31.7%) 14 (23.3%) 10 (22.2%)  
Lymphovascular invasion     
Negative 36 (87.8%) 48 (80.0%) 27 (60.0%) 0.007*
Positive 5 (12.2%) 12 (20.0%) 18 (40.0%)  
Estrogen receptor/progesterone receptor expression     
Negative 20 (48.8%) 24 (40.0%) 19 (42.2%) 0.674
Positive 21 (51.2%) 36 (60.0%) 26 (57.8%)  
HER-2 overexpression     
Negative 38 (92.7%) 51 (85.0%) 29 (64.4%) 0.003*
Positive 3 (7.3%) 9 (15.0%) 16 (35.6%)  
Triple negative status     
No 23 (56.1%) 36 (60.0%) 30 (66.7%) 0.593
Yes 18 (43.9%) 24 (40.0%) 15 (33.3%)  
Tumor budding     
G1 27 (65.9%) 27 (45.0%) 9 (20.0%) <0.001*
G2 11 (26.8%) 24 (40.0%) 20 (44.4%)  
G3 3 (7.3%) 9 (15.0%) 16 (35.6%)  
Relapse     
No 37 (90.2%) 49 (81.7%) 16 (35.6%) <0.001*
Yes 4 (9.8%) 11 (18.3%) 29 (64.4%)  
Death     
No 38 (92.7%) 51 (85.0%) 25 (55.6%) <0.001*
Yes 3 (7.3%) 9 (15.0%) 20 (44.4%)  
Total 146 41 60 45  
  1. *P <0.05.