Table 4 Multivariate analysis: clinicopathological features correlated with positive cavity margins

A. Positive CMs including DCIS and invasive carcinoma

EIC

2.58

1.54–4.32

<0.001

Luminal B vs. luminal A

1.22

0.73–2.04

0.456

Luminal-HER-2 vs. luminal A

1.08

0.63–1.86

0.774

HER-2 vs. luminal A

2.60

1.48–4.57

<0.001

Triple-negative vs. luminal A

0.71

0.37–1.39

0.320

N1 vs. N0

1.43

0.92–2.20

0.109

N2 vs. N0

1.17

0.51–2.70

0.706

N3 vs. N0

3.92

1.60–9.62

0.003

B. Positive CM including DCIS only

EIC

4.50

2.59–7.84

<0.001

Luminal B vs. luminal A

2.42

1.26–4.67

0.008

Luminal-HER-2 vs. luminal A

2.06

1.07–3.99

0.032

HER-2 vs. luminal A

5.58

2.89–10.77

<0.001

Triple-negative vs. luminal A

0.64

0.22–1.87

0.414

C. Positive CM including invasive cancer only

Presence of DCIS component vs. IDC

2.19

1.04–4.63

0.040

ILC vs. IDC

2.82

1.10–7.23

0.031

Other vs. IDC

0.75

0.33–1.70

0.488

pN stage

N1 vs. N0

2.15

1.30–3.53

0.003

N2 vs. N0

1.41

0.53–3.77

0.490

N3 vs. N0

8.42

3.54–20.05

<0.001